What active ingredient in callus softeners has anti-inflammatory properties?

Salicylic acid stands out as the active ingredient in callus softeners that possesses anti-inflammatory properties. This compound belongs to a class of medications known as keratolytics, which work by promoting the shedding of the outer layer of skin. Additionally, salicylic acid helps to reduce inflammation and redness, making it beneficial for soothing irritated skin in areas with calluses. Its ability to penetrate the skin and help in the removal of excess keratin also contributes to its effectiveness in treating callused areas while calming any associated irritation.

Urea, while effective for softening and hydrating the skin, does not possess the same anti-inflammatory properties as salicylic acid. Potassium hydroxide is primarily used for its alkalinity to help dissolve keratin but does not have specific inflammation-reducing capabilities. Sodium chloride, commonly known as salt, is not involved in the softening of calluses and has limited relevance in the context of skincare treatments focused on inflammation.